• Commodity Tobacco, Anti-Cancer Plant

    For hundreds of years perhaps, our society more familiar with tobacco (Nicotiana spp., L.) as one of the supplementary materials of traditional rituals. Bleak in welcoming guests to chew betel. The world also knows this plant from the American continent as a cigarette maker, and deploy smoke a tremendous advantage. Although the accused can damage health, but probably many who do not know if these plants can actually kill pests and beat cancer.

    Tobacco is a broadleaf plant genus from the region of North America and South America. The leaves of this tree is often used as a raw material for cigarettes, either by using a pipe or rolled in the form of cigarettes or cigars. Tobacco leaf can be chewed or dikulum, and there is also a powdered tobacco smoked through the nose. The content of substances in the tobacco alkaloid nicotine is a powerful neurotoxin type when used in insects. And indeed this substance often used as the main ingredient of insecticides.


    The origin of tobacco, it turns out from the Spanish "Tabaco" and regarded as the origin of the word in the language Arawakan, in particular, in the language of the Taino in the Caribbean. Because the mentioned refers to the roll of the leaves on this plant, according to Bartolome de Las Casas, in 1552, could also be from the word "tabago". That is a kind of y-shaped pipe to inhale tobacco smoke.


    According to Oviedo, the leaves of tobacco referred to as Cohiba, but Sp. It also Tabaco. Tobacco, commonly used to define medicinal plants since 1410, which comes from the Arabic "tabbaq", who reportedly existed since the 9th century, as the name of several plants. While the word tobacco in English, could be derived from Europe, and eventually applied to similar plants that originated from America.


    Tobacco plants could also be called the genus Nicotiana, which is a branch of the family solanaceace. As well as various types of plants in the family such as eggplant and tomato, tobacco also came from the Americas, as the use of tobacco plants; at the beginning of the 16th century, some differences have been trusted varieties are still under treatment. Modern tobacco comes from two wild species of Nicotiana which are found in the eastern region of the Andean center, an area close to Bolivia and Argentina.


    As a result of agriculture, tobacco is processed from the fresh leaves. Historically, Native American culture recognize tobacco as a dry product material for the cigarette or cigar, and also sometimes smoked with a pipe. Even in other cultures such as in Indonesia, for example, tobacco sometimes disumpalkan into the mouth between the cheek and gum after chewing betel. And it turns out tobacco use can also cause harmful ketergantunan because the content of nicotine that is in it a bad impact on health. Especially if it continues to be used in the long term can cause cancer among other diseases, cardiovascular harm to the fetus and cause impotence.


    But it seems, human dependence on cigarettes is difficult abolished. Despite so many calls and slogans to stay away from this stuff, but in fact the tobacco industry even more width and mushrooming. Though the data in the United States said, about 440 thousand people die every year because there become active smoker. And 3 thousand people were forced to become victims because accidentally inhaling someone else's cigarette smoke, passive smokers, and a thousand babies die before birth from mothers who is a smoker. Not to mention there is other evidence that also indicate if the mother is also there is an active smoker who gave birth to babies with physical disabilities.


    But history says, the discovery of Columbus marks the turning point of the tobacco plant. These plants grow quickly in Europe, and has spread throughout the world via the Spanish, Portuguese, British fishermen, traders and hunters. Tobacco is believed arrived in Japan at the end of the 16th century, at which time the exchange with the Iberian country has taken place and this century is an important period in Europe.


    Then tobacco spread to various parts of the world, and perhaps many do not know the pattern and style to consume tobacco that has been developed to suit local conditions and taste in various regions. Forms of European pipe length and pipe that sprawl used in other parts of Japan and East Asian countries, hookahs and water-pipies (water pipe) close to the eastern region is an example of a variety of themes to be consumed tobacco plants that spread ranging from the American continent to the entire world.


    At present, many researchers who developed the use of tobacco. No more famous as a presenter smoke blowing pleasure from each cigarette. Tobacco eventually also be used for the benefit of agriculture and health. In the world of agriculture, tobacco is known as an effective pest control. The best plants are safe as long as you certainly acquainted with tobacco. And the women were no longer made with the devil terrifying fear of cervical cancer. Because again, the tobacco is a plant rescue.


    Uterus Cancer Deterrent
    During these negative accusations always lead to tobacco, one of them as causes of cancer. But apparently, some time ago researchers from the Center for Research Bioteknolgoi Indonesian Institute of Sciences (LIPI) DR. Arief Budi Witarto MEng, it was discovered anti-cancer proteins in tobacco. And research proposal that brought about this Doctor of Biotechnology of the Faculty of Engineering, Tokyo University of Agriculture and Technology, Japan had won an award from the DAAD and the German research agency in Jakarta Fraunhofer.

    Apparently, in the proposed research, the Ariel tries to produce proteins important "Growth Colony Stimulating Factor (GCSF) using tobacco plants (Nicotiana spp., L.) of local varieties most suitable" kenongo early maturing "of the 18 local varieties studied . And tobacco plants is not taken leaves of tobacco to produce cigarettes but used as protein GCSF-producing reactor, a hormone that stimulates blood production.
    According to Arif, a protein made by the DNA of our bodies, our DNA is enter it into tobacco via bacteria. Once signed, this plant will make proteins according to the inserted DNA. If the plant is harvested, we will mendapatkancairannya form of the protein. In addition to anticancer proteins, GSCF, he said, it could be to stimulate stem cell proliferation (stemcell) that can be developed to restore bodily function network that is damaged.


    Ariel is an expert in the field of protein engineering and has received many awards, among others Paramadina Award 2005 to the field of Science and Technology from the University of Paramadina and PII Engineering Award 2005 for the category of Best Creation Adhicipta Engineering or in Engineering of the PII / Association of Indonesian Engineers. In fact, he never received any other award of Science and Technology Award 2003 from the Indonesia Toray Science Foundation (ITSF) and Best Young Researcher Indonesia 2002 to the field of Mechanical Science and Engineering from LIPI. And had been elected with the highest score representing Indonesia along with four other young researchers from Indonesia with an official invitation from the German Government to attend the Meeting of Nobel Prize Laureates in Lindau Germany city.


    During this cervical cancer there is no antidote, but the tobacco plants could be an alternative. It's one of the benefits of tobacco plants. Based on research, the plant is capable of being a carrier of genetic development of human papilloma virus (HPV) to produce germ cells that later can be antibodies for the virus triggers cervical cancer. Even a recent study on cervical cancer cure is now being conducted by scientists from Georgetown University Medical Center (Georgetown University Medical Center) and University of North Carolina, United States.


    Apparently, after investigation, tobacco plants containing genetically engineered protein that can stimulate antibodies against HPV that cause cervical cancer. The research project was funded by three million U.S. dollars from the pockets of the central government as part of farm legislation that was recently released to Congress.


    Chief Researcher at Georgetown University, Washington DC, Dr. Kenneth Dretchen explain the idea that research including the development of antibodies against HPV. For some reason HPV do not breed well under normal conditions of microbiology. The results reveal the right environment for the development of germ cells were present in tobacco plants.


    Although that sounds weird and corny, Dretchen said it had been doing research on the HPV virus in Georgetown. But this time constraint is the lack of quantity of antibodies necessary to provide for healing on a large scale. The study was intended also to seek solutions to the development of the quantity of virus antibodies.


    Meanwhile, North Carolina State University will use the personnel, expertise in the cultivation of tobacco. They will produce and conduct tests for these antibodies, which will take 2-3 years before laboratory testing. The study is one attempt to seek treatment for cervical cancer, which until now has not known antidote.
    Treatment of cervical cancer has been done by three ways namely surgery, radiation (irradiation) and chemotherapy. Each treatment was performed according to the stage of the cancer doctors who experienced patients and with consideration of the rules and risks for the patient.


    Cervical cancer as yet unknown cause. But according to a recent study, the HPV virus is one of the trigger. HPV can infect a woman if her sexual partner contracted the virus due to mutually couple. In addition, women who have the habit of smoking is also prone to this cancer. And apparently contained nicotine tobacco substances have a tendency affects the mucous membranes in the body, including cervical mucous membrane, thus making it susceptible to cancer cells.


    Cervical cancer usually affects women of childbearing age, or ever had sex, frequent change of sexual partners, mating in the relatively young age (not yet 17 years old) and a lot of labor. In cases of cervical cancer, almost never occur in women who have never had sexual intercourse. To know the early symptoms women should routinely perform pap smears after having sex once a year, or three months after giving birth to detect the presence or absence of pre-cancer / dysplasia. The weakness of this pap smears, partly due to discharge from the vagina is inadequate to the cells in it are not terllihat. Another drawback, noted kemungkinana coloring substance used has exceeded the time limit (expire date).


    And constraints can also occur if found cases of human error, for example, the pathologist who read the results of accidental eye fatigue, resulting in errors. Will presumption cervical cancer can appear suddenly, not true. Provided frequently checked himself, the presence of HPV can be detected. Dysplasia or precancerous consists of three stages, namely mild, moderate and severe. From the stage of dysplasia into early-stage cancer, takes two years. To prove dysplasia after undergoing examination and pap smear abnormalities are found, then performed a biopsy, cancerous tissue is cut and taken for laboratory examination.


    Regarding the symptoms of cervical cancer, at the stage of dysplasia to stage I, practically without complaint. Just step on stage 1 A-3b are complaints of patients, whereas stage 4B cancer cells have spread to the brain and lungs. Cervical cancer, a disease that many women in Indonesia diidap. So there's no harm if we begin to maintain healthy early on, held a routine examination, and started to make friends with tobacco!


    Inhaling Tobacco glad Glad 

    In the homeland, for the tobacco business, becoming the champion of Lombok in terms of both quality and quantity. Virginia Tobacco Lombok is known as the best quality number 3 worldwide, tobacco under Zimbabwe and China. Apart from being exported to European countries like Germany and the Netherlands, tobacco is also developed to meet the needs of cigarette factories in Indonesia.

    Lombok tobacco actually consists of two widely known types, namely Virginia tobacco varieties derived from the land of Uncle Sam, Virginia United States, and the tobacco people commonly referred to as tobacco Glad chopped tobacco, tobacco Musk, Eskort, black tobacco, and tobacco Makopan.Sementara discussed is that many local tobacco Glad, a special distinctive taste Glad to be planted in the Village, East Lombok.


    Uh, wait a minute! Do not tell me you are a connoisseur of smoking, if you have not tried tobacco Glad. At least this is the expression of smokers who had tried tobacco Glad original. Although the type is not much and not even marketed to traditional markets though, because the amount is minimal. But the distinctive taste of tobacco was reputedly possessed extraordinary, make a lot of people hunting him like a rare commodity. Moreover, the price is quite expensive between Rp 150 thousand to USD 200 thousand to half a kilogram! Compare the price of tobacco Lombok jensi Musk, Yellow or Black the most only USD 10 thousand to USD 60 thousand to half a kilogram.


    Taru Martani 

    Although the tobacco industry was growing rapidly at this time, but the typical chopping tobacco Lombok society remains always remembered. Local tobacco trade is so smooth mengusai traditional market area in Mataram, both big markets like Mandalika Market, Market Kebon Roek, Ampenan Market, Market Inbound, Sind Market, Market Pagesangan, as well as other small markets. It could be that it tastes good or is the price that much cheaper than a cigarette manufacturer. And it turns out chopping tobacco enthusiasts from all walks of life.

    Bede's good tobacco, tobacco also vary with the Java Besuki as the embryo of a world-class cigars. Known, since 1918, Taru Martani always creates a mixture formulation tobacco flavored cigars high in order to fulfill the desire of a true cigar lover. Taru Martani currently produces 14 types of cigars which are well known throughout the world, namely Cigarillos / Treasure, Extra Cigarillos, Senoritas, Panatella, Slim Panatella, Half Corona, Corona, Super Corona / Grand Corona, Boheme, Royal, perfecto, Rothschild, and Churchill.


    In the development Taru Martani currently produces three formulations blend cigars are: Natural Cigar (pure tobacco), Flavour Cigar (tobacco with sauce / flavor Mint, Amareto, Vanilla, Rum and Hazelnut) and Mild Cigar (tobacco 'light'). Taru Martani raw materials from local tobacco Besuki, Jember, East Java. Tobacco is called Java Besuki which has a fairly prominent tobacco flavor with a blackish brown color.


    In the process, used for wrapping Java Besuki in (omblad) and outer (dekblad) cigars. As for the content (filler) used tobacco Besuki Java which has been mixed with tobacco from Havana and Brazil. The uniqueness of the manufacture of cigars Taru Martani is because all of the manufacturing process is done manually by hand. Therefore we can say every cigar is made with high precision and became the selected entries. And truly amazing.


    Currently as many as four dozen kinds of cigar production Martani Taru has now become a promising export commodity. Penetrated market for the Netherlands, Belgium, Germany, Czechoslovakia, America, Asia and in the near Taru Martani will expand into Eastern Europe and Central Europe and Asean.

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